Humatrope Lilly France 72 IU 24 mg

Product name: Humatrope
Manufacturer :Lilly France S.A.S
Presentation :cartridge powder 72 IU 24 mg + dispencer with solvent
Active chemical :somatotropinum

Humatrope by Lilly is a naturally occurring substance secreted by the anterior pituitary gland. It is essential for normal growth and development. Growth hormone (GH)is secreted by the pituitary gland since birth and the levels peak around late adolescence. In the 2nd decade of life, the levels of growth hormone began to decline. For more than 40 years growth hormone has been available to treat specific medical disorders. However, in the past 3 decades, growth hormone mania has hit the market and everyone wants to take it. The middle aged and elderly seem to think GH can reverse aging, the young teenagers want to build their bodies and the sports athletes want to perform better. Of all the drugs abused by sports athletes, Growth hormone probably ranks in the top three.

What Human Growth Hormone?

Human growth hormone, abbreviated as HGH, hGH and GH, is the hormone that activates cell production, growth, and metabolic processes within the human body. Secreted by the anterior pituitary located just inside the base of the skull, GH is responsible for working in conjunction with other hormones in the body to stimulate and regulate proper human growth and development. GH levels generally reach their all time high at puberty and significantly decline around the age of 40.

Growth hormone is readily available from many health food stores and spas. It is also widely available from many nutrient and alternative care practitioners. The growth hormones is frequently sold under other names like Genotropin®, Humatrope®, Norditropin®, Nutropin®, Saizen®, Serostim®)

Pharmacology

Most of the GH available is manufactured using recombinant DNA technology; the two types of synthetic HGH available are somatropin and somatrem.  Both synthetic types have similar pharmacological actions. The synthetic forms once injected are impossible to distinguish from the naturally occurring GH. Growth hormone acts by binding to GH receptors on various tissues and stimulate a variety of cellular actions. GH has multiple physiological effects including regulation of metabolism, maintaining fluid and electrolyte balances, increasing skeletal and muscle mass. GH levels are generally increased during stress, sleep and exercise.

 

In which conditions do GH levels change?

There are a few medical conditions that can develop if levels of GH are either too low or too high. With an excess amount of human growth hormone the body may over produce cells causing acromegaly, a condition characterized by oversized extremities, rapid and continual cell growth, and a variety of other serious health complications; or pituitary gigantism, which results in extreme height due to over secretion of GH.

 

Medical conditions caused by GH deficiency can be serious as well, leading to a variety of short stature conditions that may severely impact overall health

 

Approved clinical uses of GH

The FDA has several approved injectable preparations of HGH. The growth hormone is only available with a prescription from a licensed physician. Synthetically derived (recombinant) GH was initially approved by the FDA in 1985 for the treatment of short stature due to GH deficiency (GHD). In the following years, GH continued to gain approval for the treatment of specific clinical conditions causing short stature and other complications related to lifelong GHD such as Prader-Willi syndrome, short stature caused by chronic renal insufficiency, Turner syndrome, idiopathic short stature, and intrauterine growth retardation. The FDA has also approved GH therapy as a treatment for growth hormone deficiency attributed to the presence of pituitary tumors. Another recent approved use for GH has been to treat adults who develop the wasting syndrome of AIDS.

There is a lot of evidence that shows that injection of GH in the above mentioned disorders can result in:
     
increased muscle mass and bone density
decreased body fat
improved mentation
increased exercise performance
increased cardiovascular tolerance to stress/exercise

 

Dosing

GH is never taken orally. It is always administered as an injection- either subcutaneous or intramuscular. GH acts pretty rapidly once it is absorbed in the blood stream. The dosing of growth hormone is still not fully known. While the latest research indicates it should be based on levels of IGF, many physicians dose it based on body weight. For adults, the dosing is about 0.01-0.1 mg/kg body weight. This dosing depends on the type of product and what it is to be used for. The currently available GH either comes as a powder or a liquid. The powder is solubilized in a saline solution before injection.

 

Side effects of growth hormone

GH can cause several side effects, which are disturbing. The most common include:
     
Generalized edema
Carpal tunnel syndrome
Joint and muscle pain
Neuropathies (e.g., numbness and tingling)
Increase blood glucose levels

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